Curated database of Geroprotectors
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Compound Name
Model organism
Mean LS (%)
Median LS (%) ▲
Max LS (%)
Reference
Wortmannin
Drosophila melanogaster
4.0
5.0
39.0
20017609
Metoprolol
Mice
10.0
6.4
23314750
Nebivolol
Mice
10.0
6.4
23314750
2,4-Dinitrophenol
Mice
7.0
7.0
18505478
Aspirin
Mice
8.0
18631321
Trametinib
Drosophila melanogaster
8.0
26119340
http://www.cell.com/cell/abstract/S0092-8674(15)00707-2
Creatine
Mice
9.0
17416441
Ibuprofen
Caenorhabditis elegans
10.0
25521617
Ibuprofen
Drosophila melanogaster
10.0
0.0
25521617
Ibuprofen
Drosophila melanogaster
10.0
25521617
Resveratrol
Caenorhabiditis elegans
10.0
15254550
4′-O-Methyl Epicatechin
Caenorhabiditis elegans
13.0
11.0
10.0
http://www.sciencedirect.com/science/article/pii/S0963996911005904
Rapamycin
Mice
7.0
11.0
8.0
24409289
17-A-Estradiol
Mice
12.0
0.0
24245565
Nitroflurbiprofen
Mice
12.0
18631321
Nordihydroguaiaretic Acid
Mice
12.0
18631321
Trametinib
Drosophila melanogaster
12.0
26119340
http://www.cell.com/cell/abstract/S0092-8674(15)00707-2
Catechin
Caenorhabditis elegans
9.0
13.0
19501612
21805983
Resveratrol
Drosophila melanogaster
29.0
13.0
18.0
15328413
Epigallocatechin Gallate
Rat
13.5
23834676
Ly294002
Drosophila melanogaster
11.8
14.3
22.5
20017609
Α-Lipoic Acid
Drosophila melanogaster
12.0
15.0
6.0
15328413
Rapamycin
Mice
14.0
16.0
19.0
24409289
D-Chiro-Inositol
Drosophila melanogaster
16.7
22843669
Chloramphenicol
Caenorhabditis elegans
17.0
23698443
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