Warning! Toxic compound!
Carbonylcyanide-P-Trifluoromethoxyphenylhydrazone
CAS: 370-86-5
Name:
Carbonylcyanide-P-Trifluoromethoxyphenylhydrazone
Other names:
FCCP; Carbonyl cyanide p-trifluoromethoxyphenylhydrazone; EINECS 206-730-8; BRN 4693268
Is an ionophore that is a mobile ion carrier. It referred to as an uncoupling agent because it disrupts ATP synthesis by transporting hydrogen ions through a cell membrane before they can be used to provide the energy for oxidative phosphorylation [Wiki]
Interactions
Description
UniProt ID
Protein: Solute carrier organic anion transporter family member 1B3, Gene: SLCO1B3
Toxicity
- oral LD50 [mouse] mg/kg
- Unavailable
- oral LD50 [rat] mg/kg
- Unavailable
- oral LD50 [rabbit] mg/kg
- Unavailable
Effects on organism
No dataAntibacterial
No
Antifungal
No
Antiviral
No
Longevity mechanisms activation
No dataSuppression of aging mechanisms
No dataRelation to biomarkers of Aging
Data not available
Relation to aging associated genes
No data available
Model organism
ModelCaenorhabditis elegans
SrainN2
Sex—
Age of treatment—
Experimental conditions
Agar nematode growth medium + E. coli OP50Life Extension
- Mean LS (%)
- 38.46
- Median LS (%)
- —
- Mortality rate derease (%)
- —
- Max LS (%)
- —
- Cell CLS
- —
- Cell RLS
- —
Concentration wth maximum effect
50 mkM
More info about experiment
Opposite effectNo